Benzopyran



















Benzopyran

4H-Chromen.svg
Identifiers

CAS Number



  • 254-04-6 ☒N


3D model (JSmol)


  • Interactive image


ChemSpider


  • 10651828 ☑Y



PubChem CID


  • 9211


UNII

  • 7U3W6XRV5U





Properties

Chemical formula


C9H8O

Molar mass
132.16 g·mol−1

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).


☒N verify (what is ☑Y☒N ?)

Infobox references


Benzopyran is a polycyclic organic compound that results from the fusion of a benzene ring to a heterocyclic pyran ring.


According to current IUPAC nomenclature, the name chromene used in previous recommendations is retained; however, systematic ‘benzo’ names, for example 2H-1-benzopyran, are preferred IUPAC names for chromene, isochromene, chromane, isochromane, and their chalcogen analogues.[1] There are two isomers of benzopyran that vary by the orientation of the fusion of the two rings compared to the oxygen, resulting in 1-benzopyran (chromene) and 2-benzopyran (isochromene)—the number denotes where the oxygen atom is located by standard naphthalene-like nomenclature.


Some benzopyrans have shown anticancerous activity in vitro.[2]


The radical form of benzopyran is paramagnetic. The unpaired electron is delocalized over the whole benzopyran molecule, rendering it less reactive than one would expect otherwise, a similar example is the cyclopentadienyl radical. Commonly, benzopyran is encountered in the reduced state, in which it is partially saturated with one hydrogen atom, introducing a tetrahedral CH2 group in the pyran ring. Therefore, there are many structural isomers owing to the multiple possible positions of the oxygen atom and the tetrahedral carbon atom:







Structural isomers of chromene


2H-Chromen.svg
2H-chromene
(2H-1-benzopyran)


4H-Chromen.svg
4H-chromene
(4H-1-benzopyran)

5H-chromene

7H-chromene

8aH-chromene



Structural isomers of isochromene


1H-Isochromen.svg
1H-isochromene
(1H-2-benzopyran)


3H-Isochromen.svg
3H-isochromene
(3H-2-benzopyran)


See also


  • Benzofuran

  • Benzopyrone


References




  1. ^ "Front Matter". Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. pp. P001–P004. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4..mw-parser-output cite.citationfont-style:inherit.mw-parser-output .citation qquotes:"""""""'""'".mw-parser-output .citation .cs1-lock-free abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-subscription abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registrationcolor:#555.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration spanborder-bottom:1px dotted;cursor:help.mw-parser-output .cs1-ws-icon abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center.mw-parser-output code.cs1-codecolor:inherit;background:inherit;border:inherit;padding:inherit.mw-parser-output .cs1-hidden-errordisplay:none;font-size:100%.mw-parser-output .cs1-visible-errorfont-size:100%.mw-parser-output .cs1-maintdisplay:none;color:#33aa33;margin-left:0.3em.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-formatfont-size:95%.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-leftpadding-left:0.2em.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-rightpadding-right:0.2em


  2. ^ Stevenson, Alexander J; Ager, Eleanor I; Proctor, Martina A; Škalamera, Dubravka; Heaton, Andrew; Brown, David; Gabrielli, Brian G (2018). "Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo". Scientific Reports. 8 (1): 5144. doi:10.1038/s41598-018-22882-w. PMC 5865165. PMID 29572477.









-

這個網誌中的熱門文章

How to read a connectionString WITH PROVIDER in .NET Core?

圖片
6 I added .AddJsonFile("Connections.json", optional: true, reloadOnChange: true) in public Startup(IHostingEnvironment env) Connections.json contains: "ConnectionStrings": "DefaultConnection": "Server=(localdb)\mssqllocaldb;Database=DATABASE;Trusted_Connection=True;MultipleActiveResultSets=true", "COR-W81-101": "Data Source=DATASOURCE;Initial Catalog=P61_CAFM_Basic;User Id=USERID;Password=PASSWORD;Persist Security Info=False;MultipleActiveResultSets=False;Packet Size=4096;", "COR-W81-100": "Data Source=DATASOURCE;Initial Catalog=Post_PS;User Id=USERID;Password=PASSWORD;Persist Security Info=False;MultipleActiveResultSets=False;Packet Size=4096;", "MSEDGEWIN10": "Data Source=DATASOURCE; Initial Catalog=COR_Basic; Persist Security Info=False;Integrated Security=true;MultipleActiveResultSets=False;Packet Size=4096;Application Name="COR_Basic"", "server&qu
閱讀完整內容

In R, how to develop a multiplot heatmap.2 figure showing key labels successfully

圖片
1 2 I'm trying to develop a multiplot heatmap.2 saved to a pdf. I'm having some success but the axis labels are getting chopped off. Subplot titles are also desirable but again the labels are getting chopped. Here's my reproducible code: library(gridExtra) library(grid) library(gridGraphics) library(gplots) Col = colorRampPalette(c("red","orange","yellow", "white")) grab_grob <- function() grid.echo() grid.grab() par(cex.main=0.1, mar = c(1,1,1,1) ) #data<-read.table("heatmap.input.matrix.data.txt") lmat = rbind(c(2,3),c(4,1),c(4,1)) lwid = c(2.5,4) lhei = c(0.5,4,3) labRowvec <- c(rep(NULL, dim(matrix(runif(1000, 1,10),ncol=50))[1])) labColvec <- c(rep(NULL, dim(matrix(runif(1000, 1,10),ncol=50))[2])) gl <- lapply(1:12, function(i) heatmap.2(matrix(runif(1000, 1,10),ncol=50), dendrogram = "none",offsetRow=-0.5, offsetCol=-1,srtCol=0, density="density", lmat =lmat,lhei = l
閱讀完整內容

Museum of Modern and Contemporary Art of Trento and Rovereto

圖片
Art museum in Rovereto TN, Italy Museum of Modern and Contemporary Art of Trento and Rovereto Museo d'arte moderna e contemporanea di Trento e Rovereto MART, Entrance Location Corso Angelo Bettini, 43, 38068 Rovereto TN, Italy Coordinates 45°53′38″N 11°02′42″E  /  45.8940°N 11.0450°E  / 45.8940; 11.0450 Coordinates: 45°53′38″N 11°02′42″E  /  45.8940°N 11.0450°E  / 45.8940; 11.0450 Type Art museum Director Gianfranco Maraniello Public transit access Trento train station. Taxis outside station. Website mart.trento.it The Museum of Modern and Contemporary Art of Trento and Rovereto (MART) ( Museo d'Arte Moderna e Contemporanea di Trento e Rovereto , in Italian) is a museum centre in the Italian province of Trento. The main site is in Rovereto, and contains mostly modern and contemporary artworks, including works from renowned Giorgio Morandi, Giorgio de Chirico, Felice Casorati, Carlo Carrà and Fortunato Depero. Fortunato Depero's house in Rovereto (known as Casa d
閱讀完整內容